Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of <5/10/1.4/15 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,450.00 | |
50 mg | 6-8 weeks | $ 1,890.00 | |
100 mg | 6-8 weeks | $ 2,670.00 |
Description | Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM. |
In vitro | The cyclic hydrazide 28(Helioxanthin 8-1) showed the most potent anti-HBV activity among those helioxanthin analogues tested. In addition, compound 28 exhibited moderately potent activity against HIV. It would therefore be promising to study helioxanthin analogues that contain a six-membered ring instead of the five-membered ring found in the lactam [1]. 8-1 exhibited effective inhibition on DHBV replication. The combination of 8-1 with 3TC resulted in the additional anti-DHBV activity. Viral induced cells displayed higher susceptibility to 8-1 treatment than non-induced cells. HBV X protein might not be an essential factor in the initiation of the biological activity of 8-1, as demonstrated by its absence in DHBV [2]. |
Synonyms | Helioxanthin analogue 8-1 |
Molecular Weight | 376.32 |
Formula | C20H12N2O6 |
CAS No. | 840529-13-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (26.57 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Helioxanthin 8-1 840529-13-7 Others Helioxanthin 8 1 Helioxanthin analogue 8-1 Helioxanthin 81 inhibitor inhibit