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Lapaquistat

Name: Lapaquistat
Brand: TargetMol
SKU: T15710
Price: 30 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T15710Cas No. 189059-71-0

Alias T-91485

Lapaquistat is a cholesterol biosynthesis inhibitor and is the active metabolite of TAK-475. Lapaquistat can reduce statin-induced myotoxicity in lipid-lowering therapy.

Lapaquistat

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Catalog No. T15710Alias T-91485Cas No. 189059-71-0

Lapaquistat is a cholesterol biosynthesis inhibitor and is the active metabolite of TAK-475. Lapaquistat can reduce statin-induced myotoxicity in lipid-lowering therapy.

Pack Size	Price	Availability
25 mg	2.299 €	10-14 weeks
50 mg	3.021 €	10-14 weeks
100 mg	4.085 €	10-14 weeks

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Product Introduction

Bioactivity

Description	Lapaquistat is a cholesterol biosynthesis inhibitor and is the active metabolite of TAK-475. Lapaquistat can reduce statin-induced myotoxicity in lipid-lowering therapy.
Alias	T-91485

Chemical Properties

Molecular Weight	603.1
Formula	C₃₁H₃₉ClN₂O₈
Cas No.	189059-71-0
Relative Density.	1.261g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 25 mg/mL (41.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6581 mL	8.2905 mL	16.5810 mL	82.9050 mL
5 mM	0.3316 mL	1.6581 mL	3.3162 mL	16.5810 mL
10 mM	0.1658 mL	0.8290 mL	1.6581 mL	8.2905 mL
20 mM	0.0829 mL	0.4145 mL	0.8290 mL	4.1452 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

T 91485LapaquistatT91485