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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Lipoamide-PEG11-Mal is a PEG-based linker used in PROTACs, joining two essential ligands crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system [within cells]. |
In vitro | PROTACs comprise two distinct ligands linked together: one binds an E3 ubiquitin ligase, and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 884.11 |
Formula | C39H69N3O15S2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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