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Lipoamide-PEG3-Mal is a PEG-based linker for PROTACs that joins two essential ligands, which are crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Lipoamide-PEG3-Mal is a PEG-based linker for PROTACs that joins two essential ligands, which are crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, while the other binds to the target protein. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 559.74 |
Formula | C25H41N3O7S2 |
Cas No. | 1314378-19-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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