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MB-07344

Catalog No. T11954Cas No. 852947-39-8

MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.

MB-07344
Other Forms of MB-07344:
MB-07344 sodiumT11954L
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MB-07344

Catalog No. T11954Cas No. 852947-39-8
MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
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Product Introduction

Bioactivity
Description
MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
Targets&IC50
THRβ:ki: 2.17 nM
In vivo
MB-07344 (0.05 mg/kg;?i.v.;?3 times per week for 3 weeks) results in additive??and adjunctive activity when given in combination with Atorvastatin in normal rabbits.
Chemical Properties
Molecular Weight364.37
FormulaC19H25O5P
Cas No.852947-39-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

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