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MGAT2-IN-2

Catalog No. T12029Cas No. 1710630-11-7

MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) with an IC50 of 3.4 nM.

MGAT2-IN-2

MGAT2-IN-2

Catalog No. T12029Cas No. 1710630-11-7
MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) with an IC50 of 3.4 nM.
Pack SizePriceAvailabilityQuantity
25 mg$1,9708-10 weeks
50 mg$2,5808-10 weeks
100 mg$3,4008-10 weeks
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Product Introduction

Bioactivity
Description
MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) with an IC50 of 3.4 nM.
Targets&IC50
MGAT2:3.4 nM
In vitro
MGAT2-IN-2 exhibits potent MGAT2 inhibitory activity with an IC50 value of 3.4 nM and a ligand lipophilicity efficiency (LLE) value of 5.4[1].
In vivo
MGAT2-IN-2 elevates plasma TG levels during the oral fat tolerance test in C57BL/6J mice when administered orally at doses of 3, 10, and 30 mg/kg, 6 hours before the oil challenge.
Chemical Properties
Molecular Weight580.53
FormulaC26H21F5N4O4S
Cas No.1710630-11-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

MGAT-2-IN-2MGAT2IN2MGAT2-IN-2MGAT2 IN 2
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