Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML241 is a potent and selective inhibitors of p97 ATPase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 4-6 weeks | $ 78.00 | |
10 mg | 4-6 weeks | $ 126.00 | |
25 mg | 4-6 weeks | $ 277.00 | |
50 mg | 4-6 weeks | $ 468.00 |
Description | ML241 is a potent and selective inhibitors of p97 ATPase. |
Kinase Assay | EPZ015666 is serially diluted threefold from 1,000 to 0.051 nM and spotted into a 384-well polypropylene V-bottom microplate. 3H-SAM is serially diluted twofold in assay buffer for a seven-point dilution series with a top concentration of 700 nM (final assay concentration). Reactions are initiated by the addition of 4 nM enzyme and 40 nM peptide (final assay concentrations for both). Reactions are incubated for 60 min and quenched by the addition of 10 μL per well of 600 μM unlabeled SAM in assay buffer (final assay concentration). For the peptide competition, EPZ015666 is serially diluted threefold from 1,000 to 0.051 nM and spotted into a 384-well polypropylene V-bottom microplate. Peptide is serially diluted twofold in assay buffer for a seven-point dilution series with a top concentration of 480 nM (final assay concentration). Reactions are initiated by the addition of 4 nM enzyme and 75 nM 3H-SAM (final assay concentrations for both). Reactions are incubated for 60 min, and the reactions are quenched by the addition of 10 μL per well of 600 μM unlabeled SAM in assay buffer (final assay concentration)[1]. |
Molecular Weight | 372.46 |
Formula | C23H24N4O |
CAS No. | 1346528-06-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML241 1346528-06-0 Ubiquitination p97 ML 241 ML-241 inhibitor inhibit