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Mal-PEG5-acid is a PEG-based linker for PROTACs, joining two essential ligands essential for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Description | Mal-PEG5-acid is a PEG-based linker for PROTACs, joining two essential ligands essential for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one targeting an E3 ubiquitin ligase and the other targeting the specific protein. They leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. |
Molecular Weight | 389.4 |
Formula | C17H27NO9 |
Cas No. | 1286755-26-7 |
Relative Density. | 1.249 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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