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N3PT

Name: N3PT
Brand: TargetMol
SKU: T12158
Price: 30 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T12158Cas No. 13860-66-7

Alias N3-pyridyl thiamine

N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)

N3PT

Catalog No. T12158Alias N3-pyridyl thiamineCas No. 13860-66-7

N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)

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Product Introduction

Bioactivity

Description	N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)
Alias	N3-pyridyl thiamine

Chemical Properties

Molecular Weight	336.28
Formula	C₁₃H₁₉Cl₂N₃OS
Cas No.	13860-66-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 2.86 mg/mL (8.50 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9737 mL	14.8686 mL	29.7371 mL	148.6856 mL
5 mM	0.5947 mL	2.9737 mL	5.9474 mL	29.7371 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-3PTN3PT