Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SOS1-IN-1 is an inhibitor of SOS1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 242.00 | |
5 mg | 5 days | $ 297.00 | |
25 mg | 6-8 weeks | $ 987.00 | |
50 mg | 6-8 weeks | $ 1,360.00 | |
100 mg | 6-8 weeks | $ 1,860.00 |
Description | SOS1-IN-1 is an inhibitor of SOS1. |
In vitro | SOS1-IN-1 (40 μM) and NSC-658497(30 μM) result in growth inhibitory rate of 29% and 8% respectively. The combination treatment results in growth inhibitory rate of 54%, showing the synergistic effect of SOS1-IN-1 and NSC-658497 on cell growth inhibition. It is showed that the treatment with NSC-658497 at 40 μM for 2 hours alone or in combìnation with the treatment with 40 μM of SOS1-IN-1 overnight resulted in lower expression levels of P-AKT and P-ERK. The treatment wlth 40 μM of SOS1-IN-1 overnight resulted in lower expression levels of P-ERK. |
Synonyms | SOS1-IN-1 |
Molecular Weight | 325.36 |
Formula | C22H15NO2 |
CAS No. | 4551-00-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12.5 mg/mL (38.42 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NSC-70220 4551-00-2 MAPK Raf NSC 70220 NSC70220 SOS1-IN-1 inhibitor inhibit