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Nivolumab

Catalog No. T9907   CAS 946414-94-4

Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune checkpoint inhibitory and antineoplastic activities.

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Nivolumab Chemical Structure
Nivolumab, CAS 946414-94-4
Pack Size Availability Price/USD Quantity
1 mg In stock $ 182.00
5 mg In stock $ 449.00
10 mg In stock $ 663.00
25 mg In stock $ 1,050.00
50 mg In stock $ 1,390.00
100 mg In stock $ 1,880.00
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AntibodyUnit: 10.1 mg/mL
Purity: 98%
AntibodyUnit: 10.2 mg/mL
Purity: 98%
AntibodyUnit: 10.2 mg/mL
Purity: 98%
AntibodyUnit: 10.2 mg/mL
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune checkpoint inhibitory and antineoplastic activities.
Molecular Weight 146 kDa
CAS No. 946414-94-4

Storage

store at low temperature

store at -20 ℃

TargetMolReferences and Literature

1. Sundar R, et al. Nivolumab in NSCLC: latest evidence and clinical potential. Ther Adv Med Oncol. 2015 Mar;7(2):85-96. 2. Wang C, et al. In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates. Cancer Immunology Research. 2014 Sep;2(9):846-56.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Nivolumab 946414-94-4 Apoptosis Cell Cycle/Checkpoint Immunology/Inflammation PD-1/PD-L1 inhibitor inhibit

 

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