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SDZ 220-581

SDZ 220-581
SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
Catalog No. T12889Cas No. 174575-17-8
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SDZ 220-581

Catalog No. T12889Cas No. 174575-17-8
SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$735 days
1 mL x 10 mM (in DMSO)$1625 days
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Other Forms of SDZ 220-581:
SDZ 220-581 hydrochlorideT12889L179411-93-9
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SDZ 220-581 Ammonium saltT12872179411-94-0
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Product Introduction

Bioactivity
Description
SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
Targets&IC50
NMDAR:pki： 7.7
Chemical Properties
Molecular Weight369.74
FormulaC16H17ClNO5P
Cas No.174575-17-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 8.57 mg/mL (23.18 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7046 mL13.5230 mL27.0460 mL135.2302 mL
5 mM0.5409 mL2.7046 mL5.4092 mL27.0460 mL
10 mM0.2705 mL1.3523 mL2.7046 mL13.5230 mL
20 mM0.1352 mL0.6762 mL1.3523 mL6.7615 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SDZ 220581SDZ 220 581SDZ 220-581
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