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SDZ 220-581

Name: SDZ 220-581
Brand: TargetMol
SKU: T12889
Price: 48 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T12889Cas No. 174575-17-8

SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

SDZ 220-581

Catalog No. T12889Cas No. 174575-17-8

SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

Pack Size	Price	Availability	Quantity
2 mg	$73	5 days
1 mL x 10 mM (in DMSO)	$162	5 days

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Product Introduction

Bioactivity

Description	SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
Targets&IC50	NMDAR:pki： 7.7

Chemical Properties

Molecular Weight	369.74
Formula	C₁₆H₁₇ClNO₅P
Cas No.	174575-17-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 8.57 mg/mL (23.18 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7046 mL	13.5230 mL	27.0460 mL	135.2302 mL
5 mM	0.5409 mL	2.7046 mL	5.4092 mL	27.0460 mL
10 mM	0.2705 mL	1.3523 mL	2.7046 mL	13.5230 mL
20 mM	0.1352 mL	0.6762 mL	1.3523 mL	6.7615 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SDZ 220581SDZ 220 581SDZ 220-581