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SDZ 220-581 hydrochloride

Catalog No. T12889LCas No. 179411-93-9

SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

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Pack Size	Price	Availability	Quantity
2 mg	$73	5 days
1 mL x 10 mM (in DMSO)	$186	5 days

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Product Introduction

Bioactivity

Description

SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

Chemical Properties

Molecular Weight	406.2
Formula	C16H18Cl2NO5P
Cas No.	179411-93-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mg/mL (12.31 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4618 mL	12.3092 mL	24.6184 mL	123.0921 mL
5 mM	0.4924 mL	2.4618 mL	4.9237 mL	24.6184 mL
10 mM	0.2462 mL	1.2309 mL	2.4618 mL	12.3092 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc