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SDZ 220-581 hydrochloride

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Catalog No. T12889LCas No. 179411-93-9

SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

SDZ 220-581 hydrochloride
Other Forms of SDZ 220-581 hydrochloride:

SDZ 220-581 hydrochloride

😃Good
Catalog No. T12889LCas No. 179411-93-9
SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
Pack SizePriceAvailabilityQuantity
2 mg69 €5 days
1 mL x 10 mM (in DMSO)176 €5 days
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Product Introduction

Bioactivity
Description
SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).
Targets&IC50
NMDAR:pki： 7.7
Chemical Properties
Molecular Weight406.2
FormulaC16H18Cl2NO5P
Cas No.179411-93-9
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (12.31 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4618 mL12.3092 mL24.6184 mL123.0921 mL
5 mM0.4924 mL2.4618 mL4.9237 mL24.6184 mL
10 mM0.2462 mL1.2309 mL2.4618 mL12.3092 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

SDZ 220 581 hydrochlorideSDZ 220581 hydrochlorideSDZ 220-581 Hydrochloride
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