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SPK-601

Catalog No. T16920Cas No. 1096687-52-3
Alias LMV-601

SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.

SPK-601

SPK-601

Catalog No. T16920Alias LMV-601Cas No. 1096687-52-3
SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.
In vitro
SPK-601 (72 hours; HPV-31 cells) exhibits dose-dependent inhibition of cell growth (IC50: 16 μg/mL) and also inhibits HPV-31 specific RNA expression and DNA replication [2].
AliasLMV-601
Chemical Properties
Molecular Weight267.47
FormulaC11H16KOS2
Cas No.1096687-52-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (18.76 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7387 mL18.6937 mL37.3874 mL186.9369 mL
5 mM0.7477 mL3.7387 mL7.4775 mL37.3874 mL
10 mM0.3739 mL1.8694 mL3.7387 mL18.6937 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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