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TCO-PEG2-amine is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $57 | 5 days | |
5 mg | $91 | 5 days |
Description | TCO-PEG2-amine is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two distinct ligands—a ligand for an E3 ubiquitin ligase and a ligand for the target protein—via a linker [PROTACs]. |
Molecular Weight | 300.399 |
Formula | C15H28N2O4 |
Cas No. | 2141981-87-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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