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TCO-PEG3-TCO is a PEG-based linker crucial for PROTAC molecules, as it connects two essential ligands. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system [in cells].
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | TCO-PEG3-TCO is a PEG-based linker crucial for PROTAC molecules, as it connects two essential ligands. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system [in cells]. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [PROteolysis TArgeting Chimeras (PROTACs)]. |
Molecular Weight | 496.645 |
Formula | C26H44N2O7 |
Cas No. | 2243569-22-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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