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TP808

Name: TP808
Brand: TargetMol
SKU: T2469
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2469Cas No. 852821-06-8

Alias TP-808, TP 808

TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.

TP808

🥰Excellent

Purity: 99.43%

Catalog No. T2469Alias TP-808, TP 808Cas No. 852821-06-8

TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.

Pack Size	Price	Availability
1 mg	$56	In Stock
2 mg	$79	In Stock
5 mg	$133	In Stock
10 mg	$197	In Stock
25 mg	$333	In Stock
50 mg	$470	In Stock
100 mg	$653	In Stock
200 mg	$879	In Stock
1 mL x 10 mM (in DMSO)	$153	In Stock

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Purity:99.43%

Resource Download

COA HNMR HPLC

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.
Kinase Assay	96-well AMPK assay: AMPK activity is measured by monitoring phosphorylation of the SAMS peptide substrate (20 mM in standard assays and 100 mM in additivity assays) following a previously described protocol (Anderson et al., 2004). To determine whether A-769662-induced AMPK activation occurs in a reversible manner, AMP or A-769662 are preincubated with rat liver AMPK for 10 minutes at 20 times standard assay concentrations prior to dilution and measurement of AMPK activity.
Alias	TP-808, TP 808

Chemical Properties

Molecular Weight	482.64
Formula	C₂₆H₃₄N₂O₅Si
Cas No.	852821-06-8
Smiles	[H][C@@]12CC=CC(=O)[C@]1(O[Si](C)(C)C(C)(C)C)C(=O)c1c(OCc3ccccc3)noc1[C@H]2N(C)C
Relative Density.	1.18 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (103.6 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0719 mL	10.3597 mL	20.7194 mL	103.5969 mL
5 mM	0.4144 mL	2.0719 mL	4.1439 mL	20.7194 mL
10 mM	0.2072 mL	1.0360 mL	2.0719 mL	10.3597 mL
20 mM	0.1036 mL	0.5180 mL	1.0360 mL	5.1798 mL
50 mM	0.0414 mL	0.2072 mL	0.4144 mL	2.0719 mL
100 mM	0.0207 mL	0.1036 mL	0.2072 mL	1.0360 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TP808