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TP808

Catalog No. T2469Cas No. 852821-06-8
Alias TP-808, TP 808

TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.

TP808

TP808

Purity: 99.43%
Catalog No. T2469Alias TP-808, TP 808Cas No. 852821-06-8
TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.
Pack SizePriceAvailabilityQuantity
1 mg$56In Stock
2 mg$79In Stock
5 mg$133In Stock
10 mg$197In Stock
25 mg$333In Stock
50 mg$470In Stock
100 mg$653In Stock
200 mg$879In Stock
1 mL x 10 mM (in DMSO)$153In Stock
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Purity:99.43%
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Product Introduction

Bioactivity
Description
TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.
Kinase Assay
96-well AMPK assay: AMPK activity is measured by monitoring phosphorylation of the SAMS peptide substrate (20 mM in standard assays and 100 mM in additivity assays) following a previously described protocol (Anderson et al., 2004). To determine whether A-769662-induced AMPK activation occurs in a reversible manner, AMP or A-769662 are preincubated with rat liver AMPK for 10 minutes at 20 times standard assay concentrations prior to dilution and measurement of AMPK activity.
AliasTP-808, TP 808
Chemical Properties
Molecular Weight482.64
FormulaC26H34N2O5Si
Cas No.852821-06-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (103.6 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0719 mL10.3597 mL20.7194 mL103.5969 mL
5 mM0.4144 mL2.0719 mL4.1439 mL20.7194 mL
10 mM0.2072 mL1.0360 mL2.0719 mL10.3597 mL
20 mM0.1036 mL0.5180 mL1.0360 mL5.1798 mL
50 mM0.0414 mL0.2072 mL0.4144 mL2.0719 mL
100 mM0.0207 mL0.1036 mL0.2072 mL1.0360 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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