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Tos-PEG3, a PEG-based PROTAC linker, is suitable for synthesizing PROTACs and 3'-aminooxy oligonucleotide solid supports[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Tos-PEG3, a PEG-based PROTAC linker, is suitable for synthesizing PROTACs and 3'-aminooxy oligonucleotide solid supports[1]. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Molecular Weight | 304.36 |
Formula | C13H20O6S |
Cas No. | 77544-68-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (328.56 mM), Sonication and heating are recommended. H2O: 10 mg/mL (32.86 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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