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Trimetazidine-N-oxide

Catalog No. T13203Cas No. 1644530-89-1

Trimetazidine-N-oxide, the major active metabolite of Trimetazidine, is a selective long-chain inhibitor of 3-ketoyl coenzyme A thiolase (IC50: 75 nM) with anti-oxidant, anti-inflammatory, antinociceptive, and gastroprotective properties.

Trimetazidine-N-oxide

Trimetazidine-N-oxide

Catalog No. T13203Cas No. 1644530-89-1
Trimetazidine-N-oxide, the major active metabolite of Trimetazidine, is a selective long-chain inhibitor of 3-ketoyl coenzyme A thiolase (IC50: 75 nM) with anti-oxidant, anti-inflammatory, antinociceptive, and gastroprotective properties.
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Product Introduction

Bioactivity
Description
Trimetazidine-N-oxide, the major active metabolite of Trimetazidine, is a selective long-chain inhibitor of 3-ketoyl coenzyme A thiolase (IC50: 75 nM) with anti-oxidant, anti-inflammatory, antinociceptive, and gastroprotective properties.
Chemical Properties
Molecular Weight282.34
FormulaC14H22N2O4
Cas No.1644530-89-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Trimetazidine N oxideTrimetazidineNoxideTrimetazidine-N-oxide
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