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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Trityl-PEG10-azide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC formation. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two ligands connected by a linker: one binds to an E3 ubiquitin ligase and the other to the target protein. This configuration leverages the intracellular ubiquitin-proteasome system to selectively degrade the target proteins[1]. |
Molecular Weight | 725.87 |
Formula | C39H55N3O10 |
Cas No. | 877239-08-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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