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VH032-PEG3-acetylene

Name: VH032-PEG3-acetylene
Brand: TargetMol
SKU: T17230
Price: 92 EUR
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T17230Cas No. 2098799-80-3

VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].

VH032-PEG3-acetylene

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Catalog No. T17230Cas No. 2098799-80-3

VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].

Pack Size	Price	Availability	Quantity
2 mg	52 €	5 days

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Product Introduction

Bioactivity

Description

VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].

Chemical Properties

Molecular Weight	614.75
Formula	C₃₁H₄₂N₄O₇S
Cas No.	2098799-80-3
Relative Density.	1.237 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (81.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6267 mL	8.1334 mL	16.2668 mL	81.3339 mL
5 mM	0.3253 mL	1.6267 mL	3.2534 mL	16.2668 mL
10 mM	0.1627 mL	0.8133 mL	1.6267 mL	8.1334 mL
20 mM	0.0813 mL	0.4067 mL	0.8133 mL	4.0667 mL
50 mM	0.0325 mL	0.1627 mL	0.3253 mL	1.6267 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

VH-032-PEG3-acetyleneVH032-PEG3-acetyleneVH032PEG3acetyleneVH032 PEG3 acetylene