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VH032-PEG3-acetylene

Catalog No. T17230Cas No. 2098799-80-3

VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].

VH032-PEG3-acetylene

VH032-PEG3-acetylene

Catalog No. T17230Cas No. 2098799-80-3
VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].
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2 mg$555 days
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Product Introduction

Bioactivity
Description
VH032-PEG3-acetylene is a synthesized conjugate compound comprising a VH032-based VHL ligand and a linker, intended for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1].
Chemical Properties
Molecular Weight614.75
FormulaC31H42N4O7S
Cas No.2098799-80-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (81.33 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6267 mL8.1334 mL16.2668 mL81.3339 mL
5 mM0.3253 mL1.6267 mL3.2534 mL16.2668 mL
10 mM0.1627 mL0.8133 mL1.6267 mL8.1334 mL
20 mM0.0813 mL0.4067 mL0.8133 mL4.0667 mL
50 mM0.0325 mL0.1627 mL0.3253 mL1.6267 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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