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VU0453379

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Catalog No. T17242Cas No. 1638646-27-1

VU0453379 is a highly selective, central nervous system-penetrant, positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).

VU0453379
Other Forms of VU0453379:
VU0453379 hydrochlorideT73840
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VU0453379

😃Good
Catalog No. T17242Cas No. 1638646-27-1
VU0453379 is a highly selective, central nervous system-penetrant, positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).
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2 mg$2445 days
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Product Introduction

Bioactivity
Description
VU0453379 is a highly selective, central nervous system-penetrant, positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).
Targets&IC50
GLP1R:（EC50）1.3 μM
Chemical Properties
Molecular Weight434.57
FormulaC26H34N4O2
Cas No.1638646-27-1
Relative Density.1.28 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

VU-0453379VU 0453379VU0453379
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