Shopping Cart

Remove All

Your shopping cart is currently empty

Z-Asp-CH2-DCB

Select Batch

Purity:99.08%

Resource Download

COA HPLC HNMR

Z-Asp-CH2-DCB

Catalog No. T13378Cas No. 153088-73-4

Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$38	In Stock
10 mg	$63	In Stock
25 mg	$105	In Stock
50 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$42	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Z-Asp-CH2-DCB"

Product Introduction

Bioactivity

Description	Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.
In vitro	Z-Asp-CH2-DCB (10-100 μM) dose-dependently blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in SEB-stimulated (200 ng) PBMC. Z-Asp-CH2-DCB suppresses the production of the chemokines MCP-1, MIP-1α, and MIP-1β[1]. Z-Asp-CH2-DCB inhibits TSST-1-activated PBMC and reduces IL-1β, IL-6, TNF-α, IFN-γ, MCP-1, MIP-1α, and MIP-1β to 10, 36, 25, 10, 11, 25, and 30%, respectively[1].
In vivo	SU5416-induced septal cell apoptosis prevented byZ-Asp-CH2-DCB (1 mg; i.p.; every day for 3 weeks)[1].

Chemical Properties

Molecular Weight	454.26
Formula	C20H17Cl2NO7
Cas No.	153088-73-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 95.4 mg/mL (210 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2014 mL	11.0069 mL	22.0138 mL	110.0691 mL
5 mM	0.4403 mL	2.2014 mL	4.4028 mL	22.0138 mL
10 mM	0.2201 mL	1.1007 mL	2.2014 mL	11.0069 mL
20 mM	0.1101 mL	0.5503 mL	1.1007 mL	5.5035 mL
50 mM	0.0440 mL	0.2201 mL	0.4403 mL	2.2014 mL
100 mM	0.0220 mL	0.1101 mL	0.2201 mL	1.1007 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc