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(±)13,14-EDT

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Catalog No. T83868Cas No. 355016-19-2
Alias (±)-Dihomo-13,14-EET, (±)13,14-Epoxydocosatrienoic Acid, (±)13,14-EpDoTrE

(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.

(±)13,14-EDT

(±)13,14-EDT

😃Good
Catalog No. T83868Alias (±)-Dihomo-13,14-EET, (±)13,14-Epoxydocosatrienoic Acid, (±)13,14-EpDoTrECas No. 355016-19-2
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.
Pack SizePriceAvailabilityQuantity
25 μg$12535 days
50 μg$22535 days
100 μg$42835 days
500 μg$1,86035 days
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Product Introduction

Bioactivity
Description
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.
Alias(±)-Dihomo-13,14-EET, (±)13,14-Epoxydocosatrienoic Acid, (±)13,14-EpDoTrE
Chemical Properties
Molecular Weight348.50
FormulaC22H36O3
Cas No.355016-19-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 1 mg/ml

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