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A17

Catalog No. T88385Cas No. 2568186-47-8

A17, a bile acid analog, exhibits anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory properties. This compound diminishes fatty acid (FA) uptake and enhances FA oxidation by suppressing fatty acid translocase (Cd36) expression and stimulating AMPKα activity. A17 is applicable in NASH research.

A17

A17

Catalog No. T88385Cas No. 2568186-47-8
A17, a bile acid analog, exhibits anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory properties. This compound diminishes fatty acid (FA) uptake and enhances FA oxidation by suppressing fatty acid translocase (Cd36) expression and stimulating AMPKα activity. A17 is applicable in NASH research.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
A17, a bile acid analog, exhibits anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory properties. This compound diminishes fatty acid (FA) uptake and enhances FA oxidation by suppressing fatty acid translocase (Cd36) expression and stimulating AMPKα activity. A17 is applicable in NASH research.
Chemical Properties
Molecular Weight533.74
FormulaC31H51NO6
Cas No.2568186-47-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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