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ABAI-30

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Catalog No. T61157Cas No. 2757957-25-6

ABAI-30 is a highly potent and orally bioavailable anti-inflammatory compound that efficiently suppresses nitric oxide (NO) production in lipopolysaccharide (LPS) activated RAW264.7 cells [1].

ABAI-30

ABAI-30

😃Good
Catalog No. T61157Cas No. 2757957-25-6
ABAI-30 is a highly potent and orally bioavailable anti-inflammatory compound that efficiently suppresses nitric oxide (NO) production in lipopolysaccharide (LPS) activated RAW264.7 cells [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,520 6-8 weeks
50 mg$1,980 6-8 weeks
100 mg$2,500 6-8 weeks
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Product Introduction

Bioactivity
Description
ABAI-30 is a highly potent and orally bioavailable anti-inflammatory compound that efficiently suppresses nitric oxide (NO) production in lipopolysaccharide (LPS) activated RAW264.7 cells [1].
In vitro
In RAW264.7 cells, ABAI-30 at concentrations ranging from 10-40 µM suppresses the TLR4-pp65 and NLRP3-caspase-1 signaling pathways, resulting in the decreased expression of IL6, IL-1β, and TNFα at both the transcriptional and translational levels [1].
In vivo
In a mouse model of dextran sulfate sodium (DSS)-induced colitis, ABAI-30, administered orally at a dosage of 25 mg/kg for 5 days, exhibited significant in vivo anti-inflammatory effects with no evident toxicity [1].
Chemical Properties
Molecular Weight347.33
FormulaC17H13N7O2
Cas No.2757957-25-6
Storage & Solubility Information
StorageShipping with blue ice.

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