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Abiraterone metabolite 1

Name: Abiraterone metabolite 1
Brand: TargetMol
SKU: T13525
Rating: 4.5 (1 reviews)

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Catalog No. T13525Cas No. 1940176-03-3

Alias 3β-OH-5α-Abi

Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.

Abiraterone metabolite 1

😃Good

Catalog No. T13525Alias 3β-OH-5α-AbiCas No. 1940176-03-3

Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.

Pack Size	Price	Availability
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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Product Introduction

Bioactivity

Description	Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.
Alias	3β-OH-5α-Abi

Chemical Properties

Molecular Weight	351.52
Formula	C₂₄H₃₃NO
Cas No.	1940176-03-3
Relative Density.	1.099 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 25 mg/mL (71.12 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8448 mL	14.2239 mL	28.4479 mL	142.2394 mL
5 mM	0.5690 mL	2.8448 mL	5.6896 mL	28.4479 mL
10 mM	0.2845 mL	1.4224 mL	2.8448 mL	14.2239 mL
20 mM	0.1422 mL	0.7112 mL	1.4224 mL	7.1120 mL
50 mM	0.0569 mL	0.2845 mL	0.5690 mL	2.8448 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

3beta-OH-5alpha-AbiAbiraterone metabolite 13b-OH-5a-Abi