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Acetoacetyl Coenzyme A sodium hydrate

Name: Acetoacetyl Coenzyme A sodium hydrate
Brand: TargetMol
SKU: T36827
Price: 339 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36827

Alias Acetoacetyl-CoA sodium hydrate

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Acetoacetyl Coenzyme A sodium hydrate

😃Good

Catalog No. T36827Alias Acetoacetyl-CoA sodium hydrate

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Pack Size	Price	Availability
1 mg	$339	In Stock
5 mg	$1,180	Backorder
10 mg	$1,898	Backorder

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.
Targets&IC50	Acetate:0.021 mM (Km), Propionate:0.007 mM (Km), Butyrate:0.056 mM (Km)
In vitro	Km values for Acetoacetyl Coenzyme A sodium hydrate, acetate, and propionate were calculated from intercept and slope replots. The Km, values for Acetoacetyl Coenzyme A the acetate as substrate were 0.021 mM. The Km, values for Acetoacetyl Coenzyme A the propionate as substrate were 0.007 mM. The Km, values for Acetoacetyl Coenzyme A the butyrate as substrate were 0.056 mM. The Km, values for the carboxylic acids were remarkably high. [1]
Alias	Acetoacetyl-CoA sodium hydrate

Chemical Properties

Molecular Weight	989.61
Formula	C₂₅H₄₅N₇Na₃O₂₂P₃S
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)([O-])=O)COP(OP(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)=O)=O)=O)=O)O)C)([O-])=O)([O-])=O)N2C=NC3=C2N=CN=C3N.[Na+].[Na+].[Na+].O.O.O.O

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 8 mg/mL (8.53 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (10.1 mM), Sonication is recommended.

Solution Preparation Table

H2O/PBS (pH 7.2)

	1mg	5mg	10mg	50mg
1 mM	1.0105 mL	5.0525 mL	10.1050 mL	50.5250 mL
5 mM	0.2021 mL	1.0105 mL	2.0210 mL	10.1050 mL

PBS (pH 7.2)

	1mg	5mg	10mg	50mg
10 mM	0.1010 mL	0.5052 mL	1.0105 mL	5.0525 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

sodium HydrateAcetoacetyl-CoAAcetoacetyl Coenzyme A (sodium salt hydrate)Acetoacetyl Coenzyme A

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