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AcrB-IN-4

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Catalog No. T74829Cas No. 2890177-95-2

Efflux pump-IN-4, an AcrB efflux pump inhibitor, potentiate[s] the effects of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or display toxicity in a nematode model [1].

AcrB-IN-4

AcrB-IN-4

😃Good
Catalog No. T74829Cas No. 2890177-95-2
Efflux pump-IN-4, an AcrB efflux pump inhibitor, potentiate[s] the effects of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or display toxicity in a nematode model [1].
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Product Introduction

Bioactivity
Description
Efflux pump-IN-4, an AcrB efflux pump inhibitor, potentiate[s] the effects of antibiotics by inhibiting the efflux of Nile Red (a known substrate of AcrB). It does not disrupt the bacterial outer membrane or display toxicity in a nematode model [1].
Chemical Properties
Molecular Weight506.66
FormulaC29H34N2O4S
Cas No.2890177-95-2
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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