Shopping Cart
- Remove All
Your shopping cart is currently empty
Adecatumumab
🥰Excellent
Catalog No. T77747Cas No. 503605-66-1
Alias MT 201
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.
Adecatumumab
Adecatumumab
🥰Excellent
Catalog No. T77747Alias MT 201Cas No. 503605-66-1
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $289 | In Stock | |
| 5 mg | $788 | In Stock | |
| 10 mg | $1,230 | In Stock | |
| 25 mg | $1,850 | In Stock | |
| 50 mg | $2,490 | In Stock | |
| 100 mg | $3,360 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreSelect Batch
Concentration:2.71 mg/mL
Purity:> 95%
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer. |
| In vitro | Among human Adecatumumab and murine Adecatumumab, there are diverse kinetic binding activities observed in B16/EpCAM 3E3 cells when treated with Adecatumumab (4 μM; 18 h)[2]. Adecatumumab (0.1 ng/mL-0.1 mg/mL; 4 h) exhibits dose-dependent activity in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in natural killer (NK) cells[2]. |
| In vivo | In the B16/EpCAM xenograft tumor model in mice, both human adecatumumab and mu-adecatumumab (300 μg/mouse; i.v. bolus injection; 3 times per week) demonstrate inhibition of tumor growth[2]. Both human adecatumumab and mu-adecatumumab (300 μg/mouse; i.v. bolus injection; single dose) display a bi-exponential curve progression of serum concentration, characterized by an early distribution phase between 0 and 10 h and a terminal elimination phase[2]. |
| Alias | MT 201 |
| Molecular Weight | 147.52 kDa |
| Cas No. | 503605-66-1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Adecatumumab | purchase Adecatumumab | Adecatumumab cost | order Adecatumumab | Adecatumumab in vivo | Adecatumumab in vitro | Adecatumumab molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.