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ATP-γ-S tetrasodium
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Catalog No. T83827Cas No. 88453-52-5
Alias ATPγS tetrasodium, Adenosine-5'-O-(3-thiotriphosphate) tetrasodium, Adenosine 5'-(γ-thio)-triphosphate tetrasodium
ATP-γ-S tetrasodium (Adenosine-5'-O-(3-thiotriphosphate) tetrasodium) is a purinergic P2Y11 receptor agonist and ATP analog that induces inositol phosphate accumulation, induces insulin secretion from MIN6 pancreatic islet β-cells, and induces an increase in intracellular calcium concentration. ATP-γ-S tetrasodium inhibits the induction of the Junin virus. Junin virus-induced increase in the level of mRNA encoding bone morphogenetic protein 6 (BMP6) reduces particle-forming units (PFUs) in Junin virus-infected primary rat osteoblasts.
ATP-γ-S tetrasodium
😃Good
Catalog No. T83827Alias ATPγS tetrasodium, Adenosine-5'-O-(3-thiotriphosphate) tetrasodium, Adenosine 5'-(γ-thio)-triphosphate tetrasodiumCas No. 88453-52-5
ATP-γ-S tetrasodium (Adenosine-5'-O-(3-thiotriphosphate) tetrasodium) is a purinergic P2Y11 receptor agonist and ATP analog that induces inositol phosphate accumulation, induces insulin secretion from MIN6 pancreatic islet β-cells, and induces an increase in intracellular calcium concentration. ATP-γ-S tetrasodium inhibits the induction of the Junin virus. Junin virus-induced increase in the level of mRNA encoding bone morphogenetic protein 6 (BMP6) reduces particle-forming units (PFUs) in Junin virus-infected primary rat osteoblasts.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2600 μg | $398 | 35 days |
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Concentration:6.11 mg/mL
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Product Introduction
Bioactivity
Chemical Properties
| Description | ATP-γ-S tetrasodium (Adenosine-5'-O-(3-thiotriphosphate) tetrasodium) is a purinergic P2Y11 receptor agonist and ATP analog that induces inositol phosphate accumulation, induces insulin secretion from MIN6 pancreatic islet β-cells, and induces an increase in intracellular calcium concentration. ATP-γ-S tetrasodium inhibits the induction of the Junin virus. Junin virus-induced increase in the level of mRNA encoding bone morphogenetic protein 6 (BMP6) reduces particle-forming units (PFUs) in Junin virus-infected primary rat osteoblasts. |
| In vitro | ATP-γ-S tetrasodium enhances spinach Rubisco activase activity by enhancing autofluorescence and inducing aggregation. [1] ATP-γ-S tetrasodium (final blood concentration 50-100 μM) attenuated the inflammatory response as evidenced by a 48% reduction in cell accumulation and a 57% reduction in protein content in bronchoalveolar lavage fluid, as well as a reduction in neutrophil infiltration and a decrease in the number of neutrophils. exudation of Evans blue albumin dye in lung tissue. [3] |
| In vivo | 50 μM ATP-γ-S tetrasodium, i.v., protected lung parenchymal structures. [3] In LPS-treated mice, ATP-γ-S tetrasodium showed a dose-dependent effect on EBA exudation. [3] |
| Alias | ATPγS tetrasodium, Adenosine-5'-O-(3-thiotriphosphate) tetrasodium, Adenosine 5'-(γ-thio)-triphosphate tetrasodium |
| Molecular Weight | 611.17 |
| Formula | C10H12N5Na4O12P3S |
| Cas No. | 88453-52-5 |
| Smiles | O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+].[Na+] |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | H2O: 5 mg/mL (8.18 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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