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AF 399

Name: AF 399
Brand: TargetMol
SKU: T23646
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23646Cas No. 91533-02-7

Alias AF-399, AF399

AF 399 is a CCR4 antagonist. It reverses the tumor-promoting environment.

AF 399

🥰Excellent

Purity: 99.21%

Catalog No. T23646Alias AF-399, AF399Cas No. 91533-02-7

AF 399 is a CCR4 antagonist. It reverses the tumor-promoting environment.

Pack Size	Price	Availability
1 mg	$89	In Stock
2 mg	$126	In Stock
5 mg	$197	In Stock
10 mg	$298	In Stock
25 mg	$476	In Stock
50 mg	$678	In Stock
100 mg	$912	In Stock
200 mg	$1,190	In Stock
1 mL x 10 mM (in DMSO)	$191	In Stock

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Purity:99.21%

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COA LCMS HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	AF 399 is a CCR4 antagonist. It reverses the tumor-promoting environment.
Alias	AF-399, AF399

Chemical Properties

Molecular Weight	283.35
Formula	C₁₂H₁₇N₃O₃S
Cas No.	91533-02-7
Smiles	NS(=O)(=O)C1=CC=C(NC(=O)CN2CCCC2)C=C1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (194.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5292 mL	17.6460 mL	35.2920 mL	176.4602 mL
5 mM	0.7058 mL	3.5292 mL	7.0584 mL	35.2920 mL
10 mM	0.3529 mL	1.7646 mL	3.5292 mL	17.6460 mL
20 mM	0.1765 mL	0.8823 mL	1.7646 mL	8.8230 mL
50 mM	0.0706 mL	0.3529 mL	0.7058 mL	3.5292 mL
100 mM	0.0353 mL	0.1765 mL	0.3529 mL	1.7646 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AF 399