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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 440.49 |
Formula | C21H32N2O8 |
Cas No. | 2110449-01-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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