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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | Inquiry | 5 days |
Description | ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3, with IC50 = 0.63 μM and Ki = 0.46 μM, and is utilized in prostate cancer research [1]. |
In vitro | ALDH1A3-IN-1 (Compound 14) demonstrates significant antiproliferative effects on prostate cancer cell lines (PC3, LNCaP, and DU145) over a 96-hour treatment with IC50 values of 47 ± 6, 25 ± 1, and 61 ± 5 μM, respectively, at concentrations ranging from 0-200 μM [1]. Additionally, it reduces the viability of primary prostate epithelial cells from early-passage human tissue biopsies in a dose-dependent manner when administered at 50 and 200 μM for 72 hours, showcasing potential therapeutic action against prostate cancer [1]. |
Molecular Weight | 284.19 |
Formula | C13H18BrNO |
Cas No. | 1695970-90-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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