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Aldosterone, the primary mineralocorticoid, is synthesized and secreted by the zona glomerulosa of the adrenal cortex in response to activation of the renin-angiotensin system or high dietary potassium.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $337 | 5 days |
Description | Aldosterone, the primary mineralocorticoid, is synthesized and secreted by the zona glomerulosa of the adrenal cortex in response to activation of the renin-angiotensin system or high dietary potassium. |
In vitro | Aldosterone (1-1000 nM; 24 hours) dose-dependently inhibits interleukin-1β-stimulated nitrite production in vascular smooth muscle cells [3]. |
In vivo | Aldosterone (1 mg/Kg+1% NaCl; i.h.; once daily for 3 weeks) significantly increases systolic blood pressure (SBP), diastolic blood pressure (DBP), left ventricular systolic pressure (LVSP), and left ventricular end-diastolic pressure (LVEDP) [4]. Aldosterone (0.72 mg/kg/day; 14 days) causes a small increase (14 mmHg) in blood pressure in male mice [5]. |
Molecular Weight | 360.44 |
Formula | C21H28O5 |
Cas No. | 52-39-1 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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