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Aldosterone

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Purity:96.15%

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COA HPLC

Aldosterone

Catalog No. T19186Cas No. 52-39-1

Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.

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2 mg	$337	5 days

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Product Introduction

Bioactivity

Description	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.
In vitro	Aldosterone (1-1000 nM; 24 hours) inhibits interleukin-1β-stimulated nitrite production by vascular smooth muscle cells in a dose-dependent manner [3].
In vivo	Aldosterone (1 mg/Kg+1% NaCl; i.h.; once daily for 3 weeks) significantly increases systolic blood pressure (SBP), diastolic blood pressure (DBP), left ventricular systolic pressure (LVSP) and left ventricular end-diastolic pressure (LVEDP) [4]. Aldosterone (0.72 mg/kg/day; 14 days) causes a small increase (14 mmHg) in blood pressure in male mice [5].

Chemical Properties

Molecular Weight	360.44
Formula	C21H28O5
Cas No.	52-39-1

Storage & Solubility Information

Storage

store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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