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ALK-IN-22 (compound I-24) is a potent ALK inhibitor with an IC50 of 2.3 nM for ALK, 3.7 nM for ALKL1196M, and 2.9 nM for ALKG1202R. It down-regulates phosphorylation of ALK and its downstream proteins, inducing apoptosis. ALK-IN-22 is suitable for studying tumors.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,140 | 6-8 weeks | |
50 mg | $2,785 | 6-8 weeks | |
100 mg | $3,520 | 6-8 weeks |
Description | ALK-IN-22 (compound I-24) is a potent ALK inhibitor with an IC50 of 2.3 nM for ALK, 3.7 nM for ALKL1196M, and 2.9 nM for ALKG1202R. It down-regulates phosphorylation of ALK and its downstream proteins, inducing apoptosis. ALK-IN-22 is suitable for studying tumors. |
Molecular Weight | 477.95 |
Formula | C24H24ClN7O2 |
Cas No. | 2468219-09-0 |
Storage | Shipping with blue ice. |
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