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AM-9514

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Catalog No. T70639Cas No. 1442677-18-0

AM-9514 is a novel, potent Glucokinase (GK) activator. AM-9514 showed a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase (GK) activators represent a class of type 2 diabetes therapeutics actively pursued due to the central role that GK plays in regulating glucose homeostasis.

AM-9514

AM-9514

😃Good
Catalog No. T70639Cas No. 1442677-18-0
AM-9514 is a novel, potent Glucokinase (GK) activator. AM-9514 showed a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase (GK) activators represent a class of type 2 diabetes therapeutics actively pursued due to the central role that GK plays in regulating glucose homeostasis.
Pack SizePriceAvailabilityQuantity
25 mg2.726 €10-14 weeks
50 mg3.591 €10-14 weeks
100 mg4.940 €10-14 weeks
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Product Introduction

Bioactivity
Description
AM-9514 is a novel, potent Glucokinase (GK) activator. AM-9514 showed a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase (GK) activators represent a class of type 2 diabetes therapeutics actively pursued due to the central role that GK plays in regulating glucose homeostasis.
Chemical Properties
Molecular Weight375.42
FormulaC18H25N5O4
Cas No.1442677-18-0
Storage & Solubility Information
StorageShipping with blue ice.

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Keywords

AM-9514AM9514AM 9514HI-6 dimethanesulfate
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