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AM-Imidazole-PA-Boc

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Catalog No. T17388Cas No. 2357108-99-5

AM-Imidazole-PA-Boc is an alkyl chain-derived PROTAC linker used for the synthesis of PROTAC IRAK4 degrader-1[1].

AM-Imidazole-PA-Boc

AM-Imidazole-PA-Boc

😃Good
Catalog No. T17388Cas No. 2357108-99-5
AM-Imidazole-PA-Boc is an alkyl chain-derived PROTAC linker used for the synthesis of PROTAC IRAK4 degrader-1[1].
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2 mg$2905 days
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Product Introduction

Bioactivity
Description
AM-Imidazole-PA-Boc is an alkyl chain-derived PROTAC linker used for the synthesis of PROTAC IRAK4 degrader-1[1].
In vitro
PROTACs consist of two ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Chemical Properties
Molecular Weight254.33
FormulaC12H22N4O2
Cas No.2357108-99-5
Relative Density.1.15 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

AM-Imidazole-PA-BocAMImidazolePABocAM Imidazole PA Boc
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