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AMG 487 (S-enantiomer)

Name: AMG 487 (S-enantiomer)
Brand: TargetMol
SKU: T10297
Rating: 4.5 (1 reviews)

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Catalog No. T10297Cas No. 473720-30-8

AMG 487 S-enantiomer, the S enantiomer of AMG 487, is a CXCR3 antagonist.

AMG 487 (S-enantiomer)

😃Good

Catalog No. T10297Cas No. 473720-30-8

AMG 487 S-enantiomer, the S enantiomer of AMG 487, is a CXCR3 antagonist.

Pack Size	Price	Availability
25 mg	$1,670	6-8 weeks
50 mg	$2,180	6-8 weeks
100 mg	$2,800	6-8 weeks

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Product Introduction

Bioactivity

Description

AMG 487 S-enantiomer, the S enantiomer of AMG 487, is a CXCR3 antagonist.

Chemical Properties

Molecular Weight	603.59
Formula	C₃₂H₂₈F₃N₅O₄
Cas No.	473720-30-8
Relative Density.	1.31 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 150 mg/mL (248.51 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6568 mL	8.2838 mL	16.5675 mL	82.8377 mL
5 mM	0.3314 mL	1.6568 mL	3.3135 mL	16.5675 mL
10 mM	0.1657 mL	0.8284 mL	1.6568 mL	8.2838 mL
20 mM	0.0828 mL	0.4142 mL	0.8284 mL	4.1419 mL
50 mM	0.0331 mL	0.1657 mL	0.3314 mL	1.6568 mL
100 mM	0.0166 mL	0.0828 mL	0.1657 mL	0.8284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AMG 487 (Senantiomer)AMG 487 (S enantiomer)AMG-487AMG487AMG 487