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Amino-PEG12-CH2COOH, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Amino-PEG12-CH2COOH, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, which consist of two ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other targeting the protein of interest—utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Molecular Weight | 603.7 |
Formula | C26H53NO14 |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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