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Amino-PEG32-acid is a PEG-based linker for PROTACs, facilitating the joining of two essential ligands necessary for PROTAC molecule formation. This linker promotes selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Amino-PEG32-acid is a PEG-based linker for PROTACs, facilitating the joining of two essential ligands necessary for PROTAC molecule formation. This linker promotes selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise dual ligands linked by a connector: one binds to an E3 ubiquitin ligase and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 1498.78 |
Formula | C67H135NO34 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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