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Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 |
Targets&IC50 | A.fumigatus:2 μg/mL , Aspergillus niger 57A: 2 μg/mL , C. albicans 33/079:(MIC)1 μg/mL , Cryptococcus neoformans 451: 1 μg/mL , C.parapsilosis 937A: 8 μg/mL |
In vitro | Amphotericin X1 (compound 4) exhibits antifungal activity with significantly reduced hemolytic activity (EH50: 42 μg/mL) against mammalian erythrocytes in vitro. |
Molecular Weight | 938.118 |
Formula | C48H75NO17 |
Cas No. | 136135-57-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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