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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

Amylin, amide, rat acetate(124447-81-0,free base)

🥰Excellent
Catalog No. TP1232L

Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.

Amylin, amide, rat acetate(124447-81-0,free base)
Other Forms of Amylin, amide, rat acetate(124447-81-0,free base):
Amylin, amide, ratTP1232124447-81-0
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Amylin, amide, rat acetate(124447-81-0,free base)

🥰Excellent
Purity: 98.5%
Catalog No. TP1232L
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.
Pack SizePriceAvailabilityQuantity
1 mg$178In Stock
5 mg$436In Stock
10 mg$592In Stock
25 mg$912In Stock
50 mg$1,180In Stock
100 mg$1,660In Stock
200 mg$2,230In Stock
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Purity:98.5%
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Product Introduction

Bioactivity
Description
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.
In vivo
Amylin is an important 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. Amylin is a member of the calcitonin (CT) family of peptides, which includes CT itself, the CGRPs comprising two variants (αCGRP and βCGRP), adrenomedullin (AM) and AM2 (intermedin). Amylin is a centrally acting, neuroendocrine hormone synthesized with insulin in the beta cells of pancreatic islets. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the counter-regulatory hormone glucagon and inducing meal-ending satiety. Amylin functions as a glucoregulatory and satiety-inducing hormone, which is protective against postprandial spikes in blood glucose and overeating.[1]
Chemical Properties
Molecular Weight3980.45
FormulaC169H276N52O55S2
Smiles[H]N[C@H](C(N[C@H]1CSSC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(N4CCC[C@H]4C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC5=CC=C(C=C5)O)=O)[C@H](O)C)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(N)=O)=O)[C@H](O)C)=O)=O)=O)CC(C)C)=O)C(C)C)=O)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(N)=O)=O)CO)=O)CO)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(C)C)=O)CC6=CC=CC=C6)=O)CC(N)=O)=O)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)[C@H](O)C)=O)C)=O)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC1=O)CC(N)=O)=O)=O)C)=O)=O)=O)CCCCN.CC(O)=O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

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