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Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy and is primarily utilized in coronavirus and Ebola virus (EBOV) research.
Description | Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy and is primarily utilized in coronavirus and Ebola virus (EBOV) research. |
In vitro | Anti-virus agent 1 (compound 4i) demonstrates antiviral properties against EBOV in multiple cell lines: HeLa cells [EC50 = 1845 nM], TERT-immortalized human foreskin microvascular endothelial (HMVEC) cells (ATCC-4025) [EC50 = 367 nM], and human macrophages [EC50 = 297 nM], with a cytotoxic concentration (CC50) of 21 μM in MT4 cells (human leukemia T-cell)[1]. |
Alias | Remdesivir isopropyl ester analog, Anti-virus agent 1 |
Molecular Weight | 560.504 |
Formula | C24H29N6O8P |
Cas No. | 1911578-83-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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