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Anti-TIGIT Monoclonal Antibody-AF488
Anti-TIGIT Monoclonal Antibody-AF488
Anti-TIGIT Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIGIT. Anti-TIGIT Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Catalog No. TMAZ-0054A4
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Anti-TIGIT Monoclonal Antibody-AF488
Catalog No. TMAZ-0054A4Alias V-set and transmembrane domain-containing protein 3, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains
Anti-TIGIT Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIGIT. Anti-TIGIT Monoclonal Antibody-AF488 can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | Inquiry | Inquiry | |
| 50 μg | Inquiry | Inquiry | |
| 100 μg | Inquiry | Inquiry |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TIGIT Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TIGIT. Anti-TIGIT Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | V-set and transmembrane domain-containing protein 3, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of TIGIT overexpressed 293F cells with TMAZ-0054A4BI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type II membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TIGIT protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | TIGIT |
| Antigen Species | Human |
| Gene ID | 201633 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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