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Antibacterial agent 121
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Antibacterial agent 121
Catalog No. T61149Cas No. 474099-18-8
Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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| Description | Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1]. |
| In vitro | Antibacterial agent 121 (0.2-200 μM; 24 h) inhibits M. tuberculosis H37Rv growth in bacterial culture [1]. Antibacterial agent 121 (0-200 μM; 24 h) inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC 50 value of 4.1 μM [1]. Antibacterial agent 121 (6.25-200 μM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages [1]. Antibacterial agent 121 (25-100 μM, 4 d) inhibits M. tuberculosis M299 with an MIC 50 value of 24.8 μM [1]. Cell Viability Assay [1] Cell Line: M. tuberculosis H37Rv Concentration: 0.2-200 μM Incubation Time: 24 hours Result: Inhibited Mtb H37Rv growth with MIC 50 of 8.6 μM. Cell Viability Assay [1] Cell Line: RAW 264.7 macrophages and J774A.1 macrophages Concentration: 6.25-200 μM Incubation Time: 24 hours Result: Showed IC 50 values of 15.3 μM and 28.4 μM for TNF-α and IL-1β production, respectively. |
| Molecular Weight | 346.44 |
| Formula | C18H22N2O3S |
| Cas No. | 474099-18-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
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