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Antibacterial agent 98
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Catalog No. T61911Cas No. 2408695-41-8
Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent that inhibits the ATPase activity of Gyrase B and weakens the DNA super-helix of S. aureus. Notably, it does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance.
Antibacterial agent 98
😃Good
Catalog No. T61911Cas No. 2408695-41-8
Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent that inhibits the ATPase activity of Gyrase B and weakens the DNA super-helix of S. aureus. Notably, it does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent that inhibits the ATPase activity of Gyrase B and weakens the DNA super-helix of S. aureus. Notably, it does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance. |
| In vitro | Antibacterial agent 98 (compound g37) demonstrates antibacterial efficacy with an NIC of 0.1 μg/mL against S. aureus ATCC29213 and an IC50 of 0.15 μM targeting GyrB [1]. It also shows cytotoxicity, with IC50 values of 55.3 μM and 38.8 μM for HepG2 and HUVEC cells, respectively [1]. |
| Molecular Weight | 399.45 |
| Formula | C17H13N5O3S2 |
| Cas No. | 2408695-41-8 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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