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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Antibacterial agent 98 (compound g37) is an effective oral antibacterial agent, which can inhibit the ATPase activity of Gyrase B and weaken the DNA super-helix of S. aureus. Antibacterial agent 98 does not induce the development of MRSA (methicillin-resistant Staphylococcus aureus) resistance. |
In vitro | Antibacterial agent 98 (compound g37) exhibits antibacterial efficacy, achieving an NICs of 0.1 μg/mL against S. aureus ATCC29213 and an IC 50 of 0.15 μM targeting GyrB [1]. Additionally, this agent demonstrates cytotoxicity, with IC 50 values of 55.3 μM and 38.8 μM for HepG2 and HUVEC cells, respectively [1]. |
Molecular Weight | 399.45 |
Formula | C17H13N5O3S2 |
Cas No. | 2408695-41-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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