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Anticancer agent 101

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Catalog No. T83095Cas No. 2914922-80-6

Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].

Anticancer agent 101

Anticancer agent 101

😃Good
Catalog No. T83095Cas No. 2914922-80-6
Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].
Pack SizePriceAvailabilityQuantity
5 mgInquiry8-10 weeks
50 mgInquiry8-10 weeks
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Product Introduction

Bioactivity
Description
Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].
In vitro
Anticancer agent 101 (compound 2m; 24 and 48 h) exhibited antitumor activity, with IC50 values of 20.5 μM for Colo-205 cells and 62.9 μM for HepG2 cells [1]. At concentrations of 25 µM and 50 µM over 24 hours, Anticancer agent 101 decreased the expression of apoptotic proteins PI3K and FoXO3a, while upregulating PTEN and FoXO1 in Colo-205 cells.
Chemical Properties
Molecular Weight363.38
FormulaC19H20F3N3O
Cas No.2914922-80-6
Storage & Solubility Information
StorageShipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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