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Anticancer agent 160 (Compound 6), a natural product extracted from Parthenium hysterophorus, exhibits cytotoxicity against HCT-116 cells with an IC50 of 5.0 μM [1].
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Description | Anticancer agent 160 (Compound 6), a natural product extracted from Parthenium hysterophorus, exhibits cytotoxicity against HCT-116 cells with an IC50 of 5.0 μM [1]. |
In vitro | M109S (0.1-10000 nM , 24-48 h) inhibits cell apoptosis induced by both Bax and Bak [1]. |
In vivo | M109S, administered orally at 10mg/kg with three doses over 48 hours, protects the retina against intense light-induced photoreceptor death [1]. As a bioactive inhibitor of cell death that penetrates the blood-brain/retinal barrier, M109S can be delivered through intraperitoneal injection at 1mg/kg, intravenous injection at 5mg/kg, or oral gavage at 10mg/kg [1]. |
Storage | Shipping with blue ice. |
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