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Antifungal agent 49

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Catalog No. T78116Cas No. 1414861-21-4

Antifungal agent 49 (Example 112) demonstrates activity against Cryptococcus neoformans with a minimum inhibitory concentration (MIC) of 49 μM [1].

Antifungal agent 49

Antifungal agent 49

😃Good
Catalog No. T78116Cas No. 1414861-21-4
Antifungal agent 49 (Example 112) demonstrates activity against Cryptococcus neoformans with a minimum inhibitory concentration (MIC) of 49 μM [1].
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Product Introduction

Bioactivity
Description
Antifungal agent 49 (Example 112) demonstrates activity against Cryptococcus neoformans with a minimum inhibitory concentration (MIC) of 49 μM [1].
In vitro
Antifungal agent 49 (Example 112) demonstrated cytotoxicity in HepDES 19 cells after a 48-hour exposure, with a CC50 value of 79 μM [1].
Chemical Properties
Molecular Weight256.25
FormulaC15H12O4
Cas No.1414861-21-4
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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